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New Member
prandal42
Total Posts: 1
Registered on: ‎12-25-2011

How long does it take for Metformin to work?

Just been recently diagnose and recently put on 500mg Metformin 2x a day.  How long will it take to bring my numbers down?  Thanks

Super Advisor
carlking2
Total Posts: 2,721
Registered on: ‎04-08-2011

Re: How long does it take for Metformin to work?

Welcome to the boards, and the club no one wants to join.  I will assume for the moment that you are a new Type 2.  Met takes time to build up in your system and you might begin to see results in a week or two.  It does take up to a couple of months to reach its full effect, so please try to be patient and allow it to work.

 

Tell us about yourself....We are somewhat a nosey bunch:smileyhappy:  If you care to  please give us some idea of diet and your plans on how you are going to control this disease.  What was your Fasting number and A1c on diagnosis?  Above all please feel free to ask any questions....there are a lot of people on this board with decades of experience in managing this disease.

Thanks Rick

Diagnosed T2 4/4/2011
04/04/2011, A1c 11.2
06/27/2011, A1c 5.6
10/07/2011, A1c 5.7
1/14/2012, A1c 5.4
4/17/2012, A1c 5.4
7/27/2012, A1c 5.3
01/30/2013, A1c 5.2
08/26/2013, A1c 5.3
01/26/2014, A1c 5.5
07/25/2014, A1c 5.4

Lipids TC 203, LDL 110, VLDL 20, Triglycerides 100, HDL 73
Managed by diet and exercise along....former insulin and Metformin user
New Member
Delores12
Total Posts: 3
Registered on: ‎12-25-2011

Re: How long does it take for Metformin to work?

[ Edited ]

Hi !

 

it depends on what is causing your sugar to go up , my doctor had to switch me over to a thousand mg he is  still puzzle about my constant sugar spikes even

 

with insulin twice a day , but the good news  is 15 lbs and I'm glad about that . Working on my liquid sugar drinks i'm trying to drink o calorie dr pepper.   Must drink it extra cold to

 

mass the taste while I slowly get rid of coke products in my system

 

smileyhappy:

 

Your doctor may have up your dose because I had been talking metformin for about a year before he went up in strength.  I have an addiction to sugar and I'm trying to gain control

 

which is hard but I will master it one way or another.

 

Delores12

Trusted Contributor
morrisolder
Total Posts: 10,453
Registered on: ‎11-28-2009

Re: How long does it take for Metformin to work?

As noted, metformin may start having an effect after a couple of week, but it could also take 8-10 weeks after you reach the correct dosage. Usually they start lower than that and then increase because the gastro-disastro side effects can be pretty bad for the firs week or two...

 

But you CAN immediately affect your blood glucose levels by changing your diet, primarily by restricting carbs, and by getting more exercise, unless you are already a fitness devotee... REad a bunch here and you will find all kinds of good ideas on how to do that--or feel free to ask....

Morris

Diagnosed Type 2, with an A1c of 11.4 in 2003; averaging a 5.0 A1c since then with diet, exercise and Glipizide XL + meds for blood pressure and cholesterol. 
A bit dated, but scroll down on this page if you want to know more ...


Super Advisor
jpg391
Total Posts: 5,414
Registered on: ‎05-22-2011

Re: How long does it take for Metformin to work?

 

Welcome to the boards.

 

You already have received some good answers to your question.

 

Please read some of the threads here and ask any questions that you may have.

 

 

James G

I'm just a guy who has had type 2 diabetes for 30+ years.

"It is common sense to take a method and try it. If it fails, admit it frankly and try another. But above all, try something." – Franklin D. Roosevelt

"When you get to the end of your rope, tie a knot and hang on." – Franklin D. Roosevelt

"I always wondered why somebody doesn't do something about that. Then I realized I was somebody." – Lily Tomlin

"Happiness is a state of mind." - Walt Disney

Latest A1C 5.6 on 6/23/14

Lipids test on 8/22/13
Total Cholesterol 132
HDL Cholesterol 45
LDL Cholesterol 68
Triglycerides 94

Medications
2,000mgs X2 a day (2 weeks taking then 1 week not taking, then start over again) Capecirabine for Recital Cancer after surgery.
10mg Simvastain for Cholesterol
500mg Metformin twice a day
10 units Levemir, a long lasting insulin
81mg Asprin once a day
40mg of Quinapril (also known as Accupril) twice a day for HBP
20mg of Lexapro once a day for depression
1mg of Doxazosin once a day at bed time for a Prostate problem
30mg of Buspirone twice a day for Anxiety
Advisor
mastratton
Total Posts: 92
Registered on: ‎12-09-2011

Re: How long does it take for Metformin to work?

I just want to reiterate what Morris said. I 've been on Metformin for 13 days.  And since my diagnoses 19 days ago, my BG has been much better, and much more consistent.  I attribute that large bulk of that to my diet and exercise (I eat fewer carbs, particularly in the morning, walk on the treadmill 30 min a day, 5 days a week [except this past week]), and test far more than my doctors required me to do.

 

I'm on Metforming 500mg, 1x day (before dinner).  My disastro gastro effects lasted 2 days, and they weren't very bad, really (not in comparison to what others have experienced.)  What I can tell you is that I don't wake up in the middle of the night any more to go to the bathroom, and I largely attribute that to my Metformin and what it does ("hey, liver, quit producing extra sugar, this guy doesn't need it!)  Now, I'm not a scientist so that's really only anecdotal, but I'm reasonably certain that the med is helpful to me at night, and my diet and exercise have been helpful overall.  I think I'm benefitting from the combined effects of both (but my better numbers, I'm almost sure, are a result of diet and exercise, having lost nearly 10 pounds in 3 weeks since my diagnoses.)

 

Your mileage may vary, of course, and I only speak for my own experience.  I do not claim, nor do I presume, that my results are typical.

 

Mark

Diagnosed T2 on 12/7/22011
12/13/2011: A1C 8.6
1/19/2012: A1C 8.1
3/20/2012: A1C 5.9
6/18/2012: A1C 5.9
Metformin 500mg 2x day
Fenofibrate 200mg 1x day (high cholestoral/high triglycerides)
Lisinopril 10mg 1x day (hypertension)
Super Advisor
carlking2
Total Posts: 2,721
Registered on: ‎04-08-2011

Re: How long does it take for Metformin to work?

Prandal42,

 

Here is a link to Lizzy's blog on the subject of metformin....Might be more than you wanted to know

 

http://community.diabetes.org/t5/Lizzy-s-Lounge/All-About-Metformin/ba-p/113693

Thanks Rick

Diagnosed T2 4/4/2011
04/04/2011, A1c 11.2
06/27/2011, A1c 5.6
10/07/2011, A1c 5.7
1/14/2012, A1c 5.4
4/17/2012, A1c 5.4
7/27/2012, A1c 5.3
01/30/2013, A1c 5.2
08/26/2013, A1c 5.3
01/26/2014, A1c 5.5
07/25/2014, A1c 5.4

Lipids TC 203, LDL 110, VLDL 20, Triglycerides 100, HDL 73
Managed by diet and exercise along....former insulin and Metformin user
Responder
k_land84
Total Posts: 22
Registered on: ‎11-27-2011

Re: How long does it take for Metformin to work?

Have you talked to your doctor about the best time to take it? I am also on 500 mg a day and I started taking it at night but my doctor instructed it's better to take it with breakfast...

Frequent Advisor
sunritef
Total Posts: 2,432
Registered on: ‎11-30-2009

Re: How long does it take for Metformin to work?

Metformin takes longer to bring down your sugar levels than changing your diet. I'm Type 1, but was diagnosed as T2 originally and put on metformin.  Numbers were down in 2 days because of my diet change... when I eventually came off the metformin, no change in my numbers because I wasn't insulin resistant... point being, metformin doesn't work great in a vacuum.



You go to school to learn, not for a report card.
You use your meter to learn, not for a report card

Type 1 (LADA).. Novolog/Levemir

Adult onset T1
Super Advisor
powerwalker2
Total Posts: 5,420
Registered on: ‎11-02-2009

Re: How long does it take for Metformin to work?


prandal42 wrote:

Just been recently diagnose and recently put on 500mg Metformin 2x a day.  How long will it take to bring my numbers down?  Thanks


How high are your numbers?  The metformin effects may be almost imperceptible, and you will get more noticeable immediate results from your changes in diet and increase in exercise.  Did your doc mention those two very important lifestyle changes?  From what I've seen, metformin is just sort of a supplement to those.  it has only reduced my A1c a half a percentage point, but is constantly working in the background to help keep my numbers from going higher.  In other words: it helps, but not a lot.

Nancy ~ T2 since '98 ~ 16 yrs ~ D&E 11yrs ~ treadmill, elliptical, bike 15-20 minutes 3x/day (including evening), dumbbells/resistance training, small portions heart-healthy high-fiber/low-fat fuel/carb-counting, 500mg Glucophage XR x4, 2.5mg Glucotrol XL x6, 6000IU Vit. D/day ~ RHR 53 ~ A1cs mainly between 5.9-6.9 av. 6.5